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Lorazepam: Difference between revisions

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[[Status epilepticus|Status epilepticus]], ILAe view as a seizure that persists for a sufficient lengh of time, maybe 5-10 (focal) minutes.
[[Status epilepticus|Status epilepticus]], [[International League Against Epilepsy ||ILAe]] view as a seizure that persists for a sufficient lengh of time, maybe 5-10 (focal) minutes.
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641362/ Making SENSE--Sustained Effort Network for treatment of Status Epilepticus as a multicenter prospective registry]</ref>
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641362/ Making SENSE--Sustained Effort Network for treatment of Status Epilepticus as a multicenter prospective registry]</ref>



Revision as of 01:56, 26 January 2016

sufficient lengh of time (viewed as 30 min.period)


Status epilepticus, |ILAe view as a seizure that persists for a sufficient lengh of time, maybe 5-10 (focal) minutes. [1]

diazepam

intravenous

Other agents

lorazepam>phenitoin

midazolam

Midazolam (or lorazepam i.v.) controls effectively 63-73% early SE[2]

clonazepam

clonazepam is more lipophylic that lorazepam, but less lipophilic than diazepam(Congdon et Forsythe epilepsia 21:97(1980))

Levetirazetam

comparison

Propofol

recruitment problem
see also Trinka et al 2015 Pharmacotherapy for Status Epilepticus Drugs 1491-1521.


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