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Levetiracetam: Difference between revisions
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(S)-2-(2-Oxopyrrolidin-1-yl)butanamide is an anticonvulsant medication used to treat [[epilepsy]]. It is the S-enantiomer of [[etiracetam]], structurally similar to the prototypical nootropic drug piracetam | [[File:LeveVITAE_3813.jpg|thumb]] | ||
(S)-2-(2-Oxopyrrolidin-1-yl)butanamide is an anticonvulsant medication used to treat [[epilepsy]]. It is the S-enantiomer of [[etiracetam]], structurally similar to the prototypical nootropic drug [[piracetam]]. | |||
Levetiracetam inhibits high-voltage-activated calcium channels and reduces calcium release from intraneural stores<ref>[http://www.indianpediatrics.net/nov2013/1033.pdf newer antiepileptic drugs]</ref> | |||
==[[levetiracetam XR|Extended release]]== | ==[[levetiracetam XR|Extended release]]== | ||
[http://www.fda.gov/downloads/Drugs/DrugSafety/UCM312880.pdf | |||
[http://www.fda.gov/downloads/Drugs/DrugSafety/UCM312880.pdf Medication guide FDA] | |||
==Links== | ==Links== | ||
In myoclonic astatic epilepsy should be used with caution in children<ref>Paradoxical exacerbation of myoclonic-astatic seizures by levetiracetam in myoclonic astatic epilepsy. BMC paediatrics 15 6</ref> | |||
Li XC et al. 2017 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609163/ Clinical characteristics and electroencephalogram analysis of levetiracetam in the treatment of children with febrile seizure recurrence] | |||
Trinka E., et al 2015 | Trinka E., et al 2015 | ||
[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559580/pdf/40265_2015_Article_454.pdf Pharmacotherapy for Status Epilepticus] Drugs 75:1499 | |||
Safraski J.-P.2015 | Safraski J.-P.2015 | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519029/pdf/i1535-7511-15-2-94.pdf Is There Equipoise Between Phenytoin and Levetiracetam for Seizure Prevention in Traumatic Brain Injury?] | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519029/pdf/i1535-7511-15-2-94.pdf Is There Equipoise Between Phenytoin and Levetiracetam for Seizure Prevention in Traumatic Brain Injury?] | ||
Vrielynck P. | |||
[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716601/pdf/ndt-9-963.pdf Current and emerging treatments for absence seizures in young patients] | |||
Jackson J.-L. et al.2015 | Jackson J.-L. et al.2015 | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501738/ A Comparative Effectiveness Meta-Analysis of Drugs for the Prophylaxis of Migraine Headache] | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501738/ A Comparative Effectiveness Meta-Analysis of Drugs for the Prophylaxis of Migraine Headache] | ||
Caviness J. N. | |||
[http://www.ncbi.nlm.nih.gov/pubmed/24037428 Treatment of myoclonus] | |||
deWolfe & Szafarski | |||
[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750522/pdf/fneur-04-00121.pdf Levetiracetam use in the critical care setting] | |||
Lin CH | |||
[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672008/pdf/1471-2377-13-48.pdf Levetiracetam in the Treatment of Epileptic Seizures After Liver Transplantation] | |||
[https://karmel.miraheze.org/wiki/Levetiracetam Levetiracetam] karmel(es) | |||
==[[ATC]]== | |||
{| style="background:Ivory; color:black" border=1 cellspacing=1 cellpadding=5 | |||
|colspan=2| <center> | |||
: [[wikipedia:levetiracetam|levetiracetam]] | |||
<ref>http://www.whocc.no/atc_ddd_index/?code=N03AX14&showdescription=yes</ref></center> | |||
|} | |||
==[[West's syndrome|West syndrome]]== | |||
Mangano S et al. | |||
[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672008/pdf/1471-2377-13-48.pdf West syndrome followed by juvenile myoclonic epilepsy: a coincidental occurrence?] | |||
{{refs}} | |||
{{Wikidata|Q417227}} | |||
[[nl:levetiracetam]] | |||
[[Category:Anticonvulsants]] | [[Category:Anticonvulsants]] | ||
Latest revision as of 20:29, 20 March 2023
(S)-2-(2-Oxopyrrolidin-1-yl)butanamide is an anticonvulsant medication used to treat epilepsy. It is the S-enantiomer of etiracetam, structurally similar to the prototypical nootropic drug piracetam.
Levetiracetam inhibits high-voltage-activated calcium channels and reduces calcium release from intraneural stores[1]
Extended release
Links
In myoclonic astatic epilepsy should be used with caution in children[2]
Li XC et al. 2017 Clinical characteristics and electroencephalogram analysis of levetiracetam in the treatment of children with febrile seizure recurrence
Trinka E., et al 2015 Pharmacotherapy for Status Epilepticus Drugs 75:1499
Safraski J.-P.2015
Vrielynck P. Current and emerging treatments for absence seizures in young patients
Jackson J.-L. et al.2015
Caviness J. N. Treatment of myoclonus
deWolfe & Szafarski Levetiracetam use in the critical care setting
Lin CH
Levetiracetam in the Treatment of Epileptic Seizures After Liver Transplantation
Levetiracetam karmel(es)
ATC
West syndrome
Mangano S et al. West syndrome followed by juvenile myoclonic epilepsy: a coincidental occurrence?
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