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West's syndrome or epileptic spams is a rare condition of adult and children, it is related with Lennox–Gastaut syndrome ACTH was considered effective in treating infantile spams.  Prolonged prenatal stress or prenatal administration of corticosteroids may significantly alter seizure susceptibility 
Helena Gaufin et al.2015 Being parents with epilepsy: thoughts on its consequences and difficulties affecting their children Neuropsychiatic Disease and Treatment ;11:1291-8. doi: 10.2147/NDT.S74222. eCollection 2015.
- Diagnostic performance of 18F-FDG PET and ictal 99mTc-HMPAO SPET in pediatric temporal lobe epilepsy: quantitative analysis by statistical parametric mapping, statistical probabilistic anatomical map, and subtraction ictal SPET.
- Chung S S. 2015. A review of the efficacy and safety of extended-release topiramate in the adjunctive treatment for refractory partial-onset seizure Therapeutic Advances in Neurological Disorders (3):131-6. doi: 10.1177/1756285615578406.