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Clotiazepam
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Clotiazepam is a thieno benzodiazepine- 5-(2-Chlorphenyl)-7-ethyl-1-methyl-3H-thieno[2,3-e][1,4]diazepin-2-one - with anticonvulsant properties This agonizes the action of GABA, increasing the frequency of opening of the channel chlorinates and penetration of the ions chlorinates through the ionophore. Increase in membrane polarization decreases the probability of discharge of neurons[1]
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Refractory case of adrenergic urticaria successfully treated with clotiazepam
Pharmacological Properties of GABAA Receptors Containing γ1 Subunits
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