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Lorazepam

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sufficient lengh of time (viewed as 30 min.period)


Status epilepticus, ILAE view as a seizure that persists for a sufficient lengh of time, maybe 5-10 (focal) minutes. [1]

diazepam

intravenous

Other agents

lorazepam>phenytoin

midazolam

Midazolam (or lorazepam i.v.) controls effectively 63-73% early SE[2]

clonazepam

clonazepam is more lipophylic that lorazepam, but less lipophilic than diazepam (Congdon et Forsythe (1980) Epilepsia 21:97)

Levetirazetam

comparison

Propofol

recruitment problem
see also Trinka et al 2015 Pharmacotherapy for Status Epilepticus Drugs 1491-1521.


Q408265 at Wikidata  Interwiki via Wikidata


  1. ↑ Making SENSE--Sustained Effort Network for treatment of Status Epilepticus as a multicenter prospective registry
  2. ↑ Pharmacotherapy for Status Epilepticus
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