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Phenytoin

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Phenytoin is an anticonvulsant used in tonic clonic and partial seizures

with lower bone health disturbances[1]

higher dosis of the drug enhances the risk of hepatocellular carcinoma [2]

Toxic epidermal necrolysis was observed and therapeutic monitoring is highly recomended[3]

Persistence

Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study.

  1. ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084542/
  2. ↑ Association between antiepileptic drugs and hepatocellular carcinoma in patients with epilepsy: a population-based case-control study
  3. ↑ Phenytoin-induced toxic epidermal necrolysis: Review and recommendations
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