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Primidone

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historical considered a prodrug of phenobarbital, nevertheless it is superior against tremor [1] [2]

Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner

ATC

[3]

Links

http://www.jle.com/download/epd-303433-interactions_between_antiepileptic_drugs_and_between_antiepileptic_drugs_and_other_drugs--WDhqcX8AAQEAAG@xeO4AAAAJ-a.pdf Interactions between antiepileptic drugs, and between antiepileptic drugs and other drugs

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242891/pdf/11606_2014_Article_2907.pdf Factors Associated with Ordering Laboratory Monitoring of High-Risk Medications

Notes

  1. ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790207/pdf/tre-06-356-7522-1.pdf Essential Tremor: What We Can Learn from Current Pharmacotherapy
  2. ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766376/pdf/nihms-480525.pdf Molecular Mechanisms of Antiseizure Drug Activity at GABAA Receptors
  3. ↑ https://www.ncbi.nlm.nih.gov/pubmed/27843822 Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner
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