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Cannabis (drug)

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unknown efficacy in epilepsy [1] [2]

The Cannabis sativa plant contains([3]) more than 400 compounds, of which 100 are known as phytocannabinoids. The two cannabinoids with the highest concentrations in cannabis are delta9-tetrahydrocannabinol (Δ9-THC), responsible for most of the psychotomimetic effects of the drug, and cannabidiol (CBD), the most common non-psychoactive cannabinoid [4]

Links

Cannabinoids for pediatric epilepsy? Up in smoke or real science?

Medical Cannabis

Kolikonda et al. 2016 [5]

Entourage effect

Cannabinoids and Epilepsy

Ben Shabat et al 1998. An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity Eur J Pharmacol.


  1. ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068473/pdf/ndt-12-2605.pdf
  2. ↑ https://www.ncbi.nlm.nih.gov/pubmed/26941559 Is the medical use of cannabis a therapeutic option for children?
  3. ↑ http://www.agriculture.pa.gov/Protect/PlantIndustry/NIPPP/Documents/marijuana%20article.pdf
  4. ↑ Δ9-THC Intoxication by Cannabidiol-Enriched Cannabis Extract in Two Children with Refractory Epilepsy: Full Remission after Switching to Purified Cannabidiol
  5. ↑ Medical Cannabis for epilepsy Innovations clin.neurosci 13(3-4):
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