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Phenobarbitone
or phenobarbital is a WHO recommended AED
phenobarbital induces enzymes of the cytochrome P450 system; like phenytoin, carbamazepine, and primidone.[1]
Osteomalatia
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000640/pdf/ijms-17-01242.pdf The Impact of Anti-Epileptic Drugs on Growth and Bone Metabolism
https://www.ncbi.nlm.nih.gov/pubmed/12020260 antiepileptic drug-induced bone loss in young male patients who have seizures
Status epilepticus
http://www.mdpi.com/2077-0383/5/5/49/htm Treatment of Established Status Epilepticus
Post encephalitic epilepsy
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139974 Effect of Antiepileptic Drugs for Acute and Chronic Seizures in Children with Encephalitis
Lin K-L, Lin J-J, Hsia S-H, Chou M-L, Hung P-C, Wang H-S, et al. (2015) Effect of Antiepileptic Drugs for Acute and Chronic Seizures in Children with Encephalitis. PLoS ONE 10(10): e0139974. doi:10.1371/journal.pone.0139974
Uses
Human
Veterinary
- ↑ http://www.jfmpc.com/text.asp?2016/5/2/248/192338 Arora E, Singh H, Gupta YK. Impact of antiepileptic drugs on bone health: Need for monitoring, treatment, and prevention strategies. J Family Med Prim Care [serial online] 2016 [cited 2016 Nov 28];5:248-53.