Levetiracetam

(S)-2-(2-Oxopyrrolidin-1-yl)butanamide is an anticonvulsant medication used to treat epilepsy. It is the S-enantiomer of etiracetam, structurally similar to the prototypical nootropic drug piracetam.

Levetiracetam inhibits high-voltage-activated calcium channels and reduces calcium release from intraneural stores

Extended release

Medication guide FDA

Links

In myoclonic astatic epilepsy should be used with caution in children

Li XC et al. 2017 Clinical characteristics and electroencephalogram analysis of levetiracetam in the treatment of children with febrile seizure recurrence

Trinka E., et al 2015 Pharmacotherapy for Status Epilepticus Drugs 75:1499

Safraski J.-P.2015

• Is There Equipoise Between Phenytoin and Levetiracetam for Seizure Prevention in Traumatic Brain Injury?

Vrielynck P. Current and emerging treatments for absence seizures in young patients

Jackson J.-L. et al.2015

• A Comparative Effectiveness Meta-Analysis of Drugs for the Prophylaxis of Migraine Headache

Caviness J. N. Treatment of myoclonus

deWolfe & Szafarski Levetiracetam use in the critical care setting

Lin CH Levetiracetam in the Treatment of Epileptic Seizures After Liver Transplantation

ATC

levetiracetam

West syndrome

Mangano S et al. West syndrome followed by juvenile myoclonic epilepsy: a coincidental occurrence?

References

References:

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