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Levetiracetam
(S)-2-(2-Oxopyrrolidin-1-yl)butanamide is an anticonvulsant medication used to treat epilepsy. It is the S-enantiomer of etiracetam, structurally similar to the prototypical nootropic drug piracetam.
Levetiracetam inhibits high-voltage-activated calcium channels and reduces calcium release from intraneural stores[1]
Extended release
Links
In myoclonic astatic epilepsy should be used with caution in children[2]
Li XC et al. 2017 Clinical characteristics and electroencephalogram analysis of levetiracetam in the treatment of children with febrile seizure recurrence
Trinka E., et al 2015 Pharmacotherapy for Status Epilepticus Drugs 75:1499
Safraski J.-P.2015
Vrielynck P. Current and emerging treatments for absence seizures in young patients
Jackson J.-L. et al.2015
Caviness J. N. Treatment of myoclonus
deWolfe & Szafarski Levetiracetam use in the critical care setting
Lin CH
Levetiracetam in the Treatment of Epileptic Seizures After Liver Transplantation
ATC
West syndrome
Mangano S et al. West syndrome followed by juvenile myoclonic epilepsy: a coincidental occurrence?
- ↑ newer antiepileptic drugs
- ↑ Paradoxical exacerbation of myoclonic-astatic seizures by levetiracetam in myoclonic astatic epilepsy. BMC paediatrics 15 6
- ↑ http://www.whocc.no/atc_ddd_index/?code=N03AX14&showdescription=yes