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Phenobarbitone

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or phenobarbital is a WHO recommended AED

phenobarbital induces enzymes of the cytochrome P450 system; like phenytoin, carbamazepine, and primidone.[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000640/pdf/ijms-17-01242.pdf The Impact of Anti-Epileptic Drugs on Growth and Bone Metabolism

https://www.ncbi.nlm.nih.gov/pubmed/12020260 antiepileptic drug-induced bone loss in young male patients who have seizures

Uses

Human

Veterinary

  1. ↑ http://www.jfmpc.com/text.asp?2016/5/2/248/192338 Arora E, Singh H, Gupta YK. Impact of antiepileptic drugs on bone health: Need for monitoring, treatment, and prevention strategies. J Family Med Prim Care [serial online] 2016 [cited 2016 Nov 28];5:248-53.
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