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Levetiracetam

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(S)-2-(2-Oxopyrrolidin-1-yl)butanamide is an anticonvulsant medication used to treat epilepsy. It is the S-enantiomer of etiracetam, structurally similar to the prototypical nootropic drug piracetam.

Levetiracetam inhibits high-voltage-activated calcium channels and reduces calcium release from intraneural stores^[1]

Extended release

Medication guide FDA

Links

In myoclonic astatic epilepsy should be used with caution in children^[2]

ATC

^[3]

Trinka E., et al 2015 Pharmacotherapy for Status Epilepticus Drugs 75:1499

Safraski J.-P.2015

Is There Equipoise Between Phenytoin and Levetiracetam for Seizure Prevention in Traumatic Brain Injury?

Jackson J.-L. et al.2015

A Comparative Effectiveness Meta-Analysis of Drugs for the Prophylaxis of Migraine Headache

Caviness J. N. Treatment of myoclonus

deWolfe & Szafarski Levetiracetam use in the critical care setting

Interwiki via Wikidata

↑ newer antiepileptic drugs
↑ Paradoxical exacerbation of myoclonic-astatic seizures by levetiracetam in myoclonic astatic epilepsy. BMC paediatrics 15 6
↑ http://www.whocc.no/atc_ddd_index/?code=N03AX14&showdescription=yes

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Anticonvulsants