Primidone: Difference between revisions

Revision as of 18:43, 14 February 2017

Primidone is an anticonvulsant that is metabolized to phenylethylmalonamide (PEMA) and phenobarbital^[1], historically considered a prodrug of phenobarbital^[2], nevertheless it is superior against tremor ^[3] ^[4] Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner

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antiepileptic drugs

primidone

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References:

[1] Practice Parameter:Therapies for essential tremor Report of the Quality Standards Subcommittee of the American Academy of Neurology

[2] The history of barbiturates a century after their clinical introduction

[3] Essential Tremor: What We Can Learn from Current Pharmacotherapy

[4] Molecular Mechanisms of Antiseizure Drug Activity at GABAA Receptors

[5] ttp://www.whocc.no/atc_ddd_index/?code=N03AA03

[6] Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner

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Revision as of 17:01, 12 December 2016 (view source) Penarc (talk \| contribs) mNo edit summary ← Older edit		Revision as of 18:43, 14 February 2017 (view source) Penarc (talk \| contribs) (Category:Epilepsy) Newer edit →
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			[[Category:Anticonvulsants]]

Primidone: Difference between revisions

Revision as of 18:43, 14 February 2017

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