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Carbamazepine: Difference between revisions
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can form five polymorphic states, with low water solubility | can form five polymorphic states, with low water solubility | ||
<ref>Halliwell RA, Bhardwaj RM, Brown C, Briggs NEB, Dunn J, Robertson J,Nordon A, Florence AJ, Spray drying as a reliable route to produce metastable carbamazepine form IV, Journal of Pharmaceutical Sciences (2017), doi: 10.1016/j.xphs.2017.03.045.</ref> | <ref>Halliwell RA, Bhardwaj RM, Brown C, Briggs NEB, Dunn J, Robertson J,Nordon A, Florence AJ, Spray drying as a reliable route to produce metastable carbamazepine form IV, Journal of Pharmaceutical Sciences (2017), doi: 10.1016/j.xphs.2017.03.045.</ref> | ||
[[spina bifida]] | == == | ||
Carbamazepine teratogenicity is relatively specific to [[spina bifida]], though the risk is less than with [[valproate|valproic acid]]<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996546/ Intrauterine exposure to carbamazepine and specific congenital malformations: systematic review and case-control study]</ref> | |||
<ref>[http://www.scielosp.org/pdf/spm/v54n6/a06v54n6.pdf Malformaciones congenitas en hijos de madres epilépticas con y sin tratamiento con anticonvulsivantes]</ref> | |||
[[Stevens-Johnson syndrome]]<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372085/ HLA-B*15:21 and carbamazepine-induced Stevens-Johnson syndrome: pooled-data and in silico analysis.]</ref><ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296452/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296452/ Carbamazepine-induced Life-threatening Stevens-Johnson Syndrome and Agranulocytosis: The Maiden Case]</ref> | [[Stevens-Johnson syndrome]]<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372085/ HLA-B*15:21 and carbamazepine-induced Stevens-Johnson syndrome: pooled-data and in silico analysis.]</ref><ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296452/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296452/ Carbamazepine-induced Life-threatening Stevens-Johnson Syndrome and Agranulocytosis: The Maiden Case]</ref> | ||
<ref> | <ref>https://www.drugs.com/monograph/carbamazepine.html</ref> | ||
https://www.drugs.com/monograph/carbamazepine.html</ref> | |||
"there is any association between sexual dysfunctions and various AEDs in the treatment, except for carbamazepine | "there is any association between sexual dysfunctions and various [[antiepileptic drug|AEDs]] in the treatment, except for carbamazepine" | ||
<ref>[https://www.ncbi.nlm.nih.gov/pubmed/28315500 Relation between sexual dysfunctions and epilepsy, type of epilepsy, type of antiepileptic drugs: a prospective study]</ref> | <ref>[https://www.ncbi.nlm.nih.gov/pubmed/28315500 Relation between sexual dysfunctions and epilepsy, type of epilepsy, type of antiepileptic drugs: a prospective study]</ref> | ||
==Links== | ==Links== | ||
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[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279715/pdf/nihms614995.pdf The effects of carbamazepine on prefrontal activation in manic youth with bipolar disorder] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279715/pdf/nihms614995.pdf The effects of carbamazepine on prefrontal activation in manic youth with bipolar disorder] | ||
==[[ATC code N03|ATC]]== | |||
{| style="background:Ivory; color:black" border=1 cellspacing=1 cellpadding=5 | |||
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: [[wikipedia:carbamazepine|carbamazepine]] | |||
[http://www.whocc.no/atc_ddd_index/?code=N03AF01 N03AF01]</center> | |||
|} | |||
<ref>https://www.whocc.no/atc_ddd_index/?code=N03AF01</ref> | |||
{{refs}} | |||
[[Category:anticonvulsants]] | |||
Latest revision as of 15:15, 25 October 2024
azepine_numbering.svg.png)
structure related to imipramin
can form five polymorphic states, with low water solubility [1]
Carbamazepine teratogenicity is relatively specific to spina bifida, though the risk is less than with valproic acid[2] [3]
Stevens-Johnson syndrome[4][5] [6]
"there is any association between sexual dysfunctions and various AEDs in the treatment, except for carbamazepine" [7]
Links
Spray drying as a reliable route to produce metastable carbamazepine form IV
Antiepileptic Drugs Impair Shortening of Isolated Cardiomyocytes
Transient Splenial Lesion Following Abrupt Withdrawal of Carbamazepine
Rapamycin
Extended release
The effects of carbamazepine on prefrontal activation in manic youth with bipolar disorder
ATC
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