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Phenytoin or 5,5-Diphenyl-imidazolidine-2,4-dione is an anticonvulsant used in tonic clonic and partial seizures;

with lower bone health disturbances[1][2] higher dosis of the drug enhances the risk of hepatocellular carcinoma [3]

Toxic epidermal necrolysis was observed and therapeutic monitoring is highly recommended[4]

alteration of CyP450 may conduce to thyroid hormone function disturbances (observed phenobarbitone, carbamazepine) [5]


Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study.


Warfarin and phenytoin drug interaction with possible purple glove syndrome


A Case of Phenytoin-induced Rhabdomyolysis in Status Epilepticus


Psychosis as Harbinger of Phenytoin Toxicity

Medicinal Chemistry

Computer aided identification of sodium channel blockers in the clinical treatment of epilepsy using molecular docking tools.


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