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Kleeblattschädel syndrome

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Cloverleaf skull syndrome[1] (Kleeblattschädel syndrome) is a rare genetic disease, a deformity is etiologically and pathologically heterogeneous, so radical surgical reconstructive procedures should be planned and designed individually[2] Kleeblattschädel-Syndrom was first described by Holtermüller and Wiedermann in 1960[3]

Disease classification WHO
craniosynostosis Q75.0


Kleeblattschädel skull: a review of its history, diagnosis, associations, and treatment

History of the Kleeblattschädel deformity: origin of concepts and evolution of management in the past 50 years



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