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Valproate: Difference between revisions
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<gallery>File:Valproic acid.svg.png</gallery> | <gallery>File:Valproic acid.svg.png</gallery> | ||
Valproic acid is a carboxylic acid, <ref>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892321/pdf/BCN-7-165.pdf Hallervorden-Spatz Syndrome with Seizures </ref> | Valproic acid is a carboxylic acid, a well probed AED, with a high teratogenic potential.<ref>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892321/pdf/BCN-7-165.pdf Hallervorden-Spatz Syndrome with Seizures </ref> <ref>http://www.tijdschriftvoorpsychiatrie.nl/assets/articles/58-2016-3-artikel-solignac.pdf Een meisje met foetaal valproaatsyndroom en autismespectrumstoornis </ref> | ||
<ref>http://www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/JCP/article/Pages/2016/v77n04/v77n0420.aspx&Type=Article Shpuld women in childbearing potential be prescribed valproate?</ref> | <ref>http://www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/JCP/article/Pages/2016/v77n04/v77n0420.aspx&Type=Article Shpuld women in childbearing potential be prescribed valproate?</ref>, | ||
may alter bone metabolism | may alter bone metabolism | ||
<ref>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855910/pdf/12887_2016_Article_597.pdf Potential effects of valproate and oxcarbazepine on growth velocity and bone metabolism in epileptic children-a medical center experience</ref> | <ref>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855910/pdf/12887_2016_Article_597.pdf Potential effects of valproate and oxcarbazepine on growth velocity and bone metabolism in epileptic children-a medical center experience</ref> | ||
Revision as of 20:22, 30 June 2016
Valproic acid is a carboxylic acid, a well probed AED, with a high teratogenic potential.[1] [2] [3],
may alter bone metabolism
ATC
http://www.whocc.no/atc_ddd_index/?code=N03AX11
Links
Fanconi syndrome
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900196/pdf/10.1177_2054270415623145.pdf Progressive myoclonic epilepsy with Fanconi syndrome
Autism
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893673/pdf/srep27400.pdf Distinct Defects in Synaptic Differentiation of Neocortical Neurons in Response to Prenatal Valproate Exposure
Hipothyroidism
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864769/pdf/40681_2016_Article_12.pdf Hypothyroidism may exacerbate valproate-related hyperammonemic delirium
- ↑ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892321/pdf/BCN-7-165.pdf Hallervorden-Spatz Syndrome with Seizures
- ↑ http://www.tijdschriftvoorpsychiatrie.nl/assets/articles/58-2016-3-artikel-solignac.pdf Een meisje met foetaal valproaatsyndroom en autismespectrumstoornis
- ↑ http://www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/JCP/article/Pages/2016/v77n04/v77n0420.aspx&Type=Article Shpuld women in childbearing potential be prescribed valproate?
- ↑ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855910/pdf/12887_2016_Article_597.pdf Potential effects of valproate and oxcarbazepine on growth velocity and bone metabolism in epileptic children-a medical center experience