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Valproate: Difference between revisions

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<gallery>File:Valproic acid.svg.png</gallery>
Valproic acid is a carboxylic acid, a well probed [[Antiepileptic drug|AED]]<ref>[http://www.ncbi.nlm.nih.gov/pubmed/26608980 Long-term Effectiveness of Antiepileptic Drug Monotherapy in Partial Epileptic Patients: A 7-year Study in an Epilepsy Center in China]</ref>, with a high teratogenic potential.<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892321/pdf/BCN-7-165.pdf Hallervorden-Spatz Syndrome with Seizures ]</ref> <ref>[http://www.tijdschriftvoorpsychiatrie.nl/assets/articles/58-2016-3-artikel-solignac.pdf Een meisje met foetaal valproaatsyndroom en autismespectrumstoornis ]</ref>
Valproic acid is a carboxylic acid, a well probed AED<ref>[http://www.ncbi.nlm.nih.gov/pubmed/26608980 Long-term Effectiveness of Antiepileptic Drug Monotherapy in Partial Epileptic Patients: A 7-year Study in an Epilepsy Center in China</ref>, with a high teratogenic potential.]<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892321/pdf/BCN-7-165.pdf Hallervorden-Spatz Syndrome with Seizures ]</ref> <ref>[http://www.tijdschriftvoorpsychiatrie.nl/assets/articles/58-2016-3-artikel-solignac.pdf Een meisje met foetaal valproaatsyndroom en autismespectrumstoornis ]</ref>
<ref>[http://www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/JCP/article/Pages/2016/v77n04/v77n0420.aspx&Type=Article Should women in childbearing potential be prescribed valproate?]</ref>,  
<ref>[http://www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/JCP/article/Pages/2016/v77n04/v77n0420.aspx&Type=Article Should women in childbearing potential be prescribed valproate?]</ref>,  


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erithema nodosum was observed associated with valproate therapy
erithema nodosum was observed associated with valproate therapy
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695434/pdf/ad-27-765.pdf Erythema Nodosum Associated with Valproate ]</ref>
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695434/pdf/ad-27-765.pdf Erythema Nodosum Associated with Valproate ]</ref>
==ATC==
http://www.whocc.no/atc_ddd_index/?code=N03AX11


==Links==
==Links==
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<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623793/pdf/epj-07-1344.pdf Effectiveness of Vitamin B2 versus Sodium Valproate in Migraine Prophylaxis: a randomized clinical trial]</ref>
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623793/pdf/epj-07-1344.pdf Effectiveness of Vitamin B2 versus Sodium Valproate in Migraine Prophylaxis: a randomized clinical trial]</ref>
<references/>
 
==ATC==
http://www.whocc.no/atc_ddd_index/?code=N03AX11
 
{| style="background:Ivory; color:black" border=1 cellspacing=1 cellpadding=5
|colspan=2| <center><gallery>File:Valproic acid.svg.png</gallery>
: [[wikipedia:valproate|valproate]]
<ref>http://www.whocc.no/atc_ddd_index/?code=N03AG01</ref></center>
|}
==[[Valproate XR|extended release]]==
https://www.drugs.com/pro/divalproex-extended-release.html
 
{{refs}}
 
 
{{Wikidata|Q240642}}
[[Category:Epilepsy]]
[[Category:Anticonvulsants]]

Latest revision as of 22:47, 18 May 2019

Valproic acid is a carboxylic acid, a well probed AED[1], with a high teratogenic potential.[2] [3] [4],

may alter bone metabolism

[5] erithema nodosum was observed associated with valproate therapy [6]

Links

FLexikon:Valproinsäure

Fanconi syndrome

Progressive myoclonic epilepsy with Fanconi syndrome

Autism

Distinct Defects in Synaptic Differentiation of Neocortical Neurons in Response to Prenatal Valproate Exposure

Hipothyroidism

Hypothyroidism may exacerbate valproate-related hyperammonemic delirium

Vitamin B2

[7]

ATC

http://www.whocc.no/atc_ddd_index/?code=N03AX11

valproate
[8]

extended release

https://www.drugs.com/pro/divalproex-extended-release.html

References

References:


Q240642 at Wikidata  Interwiki via Wikidata