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Valproate: Difference between revisions
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Valproic acid is a carboxylic acid, a well probed [[Antiepileptic drug|AED]]<ref>[http://www.ncbi.nlm.nih.gov/pubmed/26608980 Long-term Effectiveness of Antiepileptic Drug Monotherapy in Partial Epileptic Patients: A 7-year Study in an Epilepsy Center in China]</ref>, with a high teratogenic potential.<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892321/pdf/BCN-7-165.pdf Hallervorden-Spatz Syndrome with Seizures ]</ref> <ref>[http://www.tijdschriftvoorpsychiatrie.nl/assets/articles/58-2016-3-artikel-solignac.pdf Een meisje met foetaal valproaatsyndroom en autismespectrumstoornis ]</ref> | Valproic acid is a carboxylic acid, a well probed [[Antiepileptic drug|AED]]<ref>[http://www.ncbi.nlm.nih.gov/pubmed/26608980 Long-term Effectiveness of Antiepileptic Drug Monotherapy in Partial Epileptic Patients: A 7-year Study in an Epilepsy Center in China]</ref>, with a high teratogenic potential.<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892321/pdf/BCN-7-165.pdf Hallervorden-Spatz Syndrome with Seizures ]</ref> <ref>[http://www.tijdschriftvoorpsychiatrie.nl/assets/articles/58-2016-3-artikel-solignac.pdf Een meisje met foetaal valproaatsyndroom en autismespectrumstoornis ]</ref> | ||
<ref>[http://www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/JCP/article/Pages/2016/v77n04/v77n0420.aspx&Type=Article Should women in childbearing potential be prescribed valproate?]</ref>, | <ref>[http://www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/JCP/article/Pages/2016/v77n04/v77n0420.aspx&Type=Article Should women in childbearing potential be prescribed valproate?]</ref>, | ||
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|colspan=2| <center> | |colspan=2| <center><gallery>File:Valproic acid.svg.png</gallery> | ||
: [[wikipedia:valproate|valproate]] | : [[wikipedia:valproate|valproate]] | ||
<ref>http://www.whocc.no/atc_ddd_index/?code=N03AG01</ref></center> | <ref>http://www.whocc.no/atc_ddd_index/?code=N03AG01</ref></center> | ||
Revision as of 22:40, 18 May 2019
Valproic acid is a carboxylic acid, a well probed AED[1], with a high teratogenic potential.[2] [3] [4],
may alter bone metabolism
[5] erithema nodosum was observed associated with valproate therapy [6]
ATC
http://www.whocc.no/atc_ddd_index/?code=N03AX11
Links
Fanconi syndrome
Progressive myoclonic epilepsy with Fanconi syndrome
Autism
Hipothyroidism
Hypothyroidism may exacerbate valproate-related hyperammonemic delirium
Vitamin B2
extended release
https://www.drugs.com/pro/divalproex-extended-release.html
- ↑ Long-term Effectiveness of Antiepileptic Drug Monotherapy in Partial Epileptic Patients: A 7-year Study in an Epilepsy Center in China
- ↑ Hallervorden-Spatz Syndrome with Seizures
- ↑ Een meisje met foetaal valproaatsyndroom en autismespectrumstoornis
- ↑ Should women in childbearing potential be prescribed valproate?
- ↑ Potential effects of valproate and oxcarbazepine on growth velocity and bone metabolism in epileptic children-a medical center experience
- ↑ Erythema Nodosum Associated with Valproate
- ↑ Effectiveness of Vitamin B2 versus Sodium Valproate in Migraine Prophylaxis: a randomized clinical trial
- ↑ http://www.whocc.no/atc_ddd_index/?code=N03AG01