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Primidone
Primidone is an anticonvulsant that is metabolized to phenylethylmalonamide (PEMA) and phenobarbital[1], historical considered a prodrug of phenobarbital[2], nevertheless it is superior against tremor [3] [4] Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner
ATC
antiepileptic drugs
Links
Interactions between antiepileptic drugs, and between antiepileptic drugs and other drugs
Factors Associated with Ordering Laboratory Monitoring of High-Risk Medications
Notes
- ↑ Practice Parameter:Therapies for essential tremor Report of the Quality Standards Subcommittee of the American Academy of Neurology
- ↑ The history of barbiturates a century after their clinical introduction
- ↑ Essential Tremor: What We Can Learn from Current Pharmacotherapy
- ↑ Molecular Mechanisms of Antiseizure Drug Activity at GABAA Receptors
- ↑ http://www.whocc.no/atc_ddd_index/?code=N03AA03
- ↑ Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner