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Primidone

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historical considered a prodrug of phenobarbital, nevertheless it is superior against tremor Cite error: Invalid <ref> tag; refs with no name must have contentEssential Tremor: What We Can Learn from Current Pharmacotherapy</ref> [1] Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner

ATC

[2]

Links

http://www.jle.com/download/epd-303433-interactions_between_antiepileptic_drugs_and_between_antiepileptic_drugs_and_other_drugs--WDhqcX8AAQEAAG@xeO4AAAAJ-a.pdf Interactions between antiepileptic drugs, and between antiepileptic drugs and other drugs

Factors Associated with Ordering Laboratory Monitoring of High-Risk Medications

Notes

  1. Molecular Mechanisms of Antiseizure Drug Activity at GABAA Receptors
  2. https://www.ncbi.nlm.nih.gov/pubmed/27843822 Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner