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Primidone
historical considered a prodrug of phenobarbital, nevertheless it is superior against tremor [1] [2]
Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner
ATC
Links
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790207/pdf/tre-06-356-7522-1.pdf Essential Tremor: What We Can Learn from Current Pharmacotherapy
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766376/pdf/nihms-480525.pdf Molecular Mechanisms of Antiseizure Drug Activity at GABAA Receptors
- ↑ https://www.ncbi.nlm.nih.gov/pubmed/27843822 Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner