Wikisage, the free encyclopedia of the second generation, is digital heritage

Primidone: Difference between revisions

From Wikisage
Jump to navigation Jump to search
No edit summary
(antiepileptic drug)
Line 1: Line 1:
Primidone is an [[AED|anticonvulsant]] that is metabolized to phenylethylmalonamide (PEMA) and [[phenobarbitone|phenobarbital]]<ref>[http://www.neurology.org/content/64/12/2008.full.pdf+html Practice Parameter:Therapies for essential tremor Report of the Quality Standards Subcommittee of the American Academy of Neurology]</ref>, historically considered a prodrug of phenobarbital<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424120/pdf/ndt-0104-329.pdf The history of barbiturates a century after their clinical introduction]</ref>, nevertheless it is superior against tremor
Primidone is an [[antiepileptic drug|anticonvulsant]] that is metabolized to phenylethylmalonamide (PEMA) and [[phenobarbitone|phenobarbital]]<ref>[http://www.neurology.org/content/64/12/2008.full.pdf+html Practice Parameter:Therapies for essential tremor Report of the Quality Standards Subcommittee of the American Academy of Neurology]</ref>, historically considered a prodrug of phenobarbital<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424120/pdf/ndt-0104-329.pdf The history of barbiturates a century after their clinical introduction]</ref>, nevertheless it is superior against tremor
<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790207/pdf/tre-06-356-7522-1.pdf Essential Tremor: What We Can Learn from Current Pharmacotherapy]</ref>
<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790207/pdf/tre-06-356-7522-1.pdf Essential Tremor: What We Can Learn from Current Pharmacotherapy]</ref>
<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766376/pdf/nihms-480525.pdf Molecular Mechanisms of Antiseizure Drug Activity at GABAA Receptors]</ref>
<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766376/pdf/nihms-480525.pdf Molecular Mechanisms of Antiseizure Drug Activity at GABAA Receptors]</ref>

Revision as of 19:01, 25 November 2016

Primidone is an anticonvulsant that is metabolized to phenylethylmalonamide (PEMA) and phenobarbital[1], historically considered a prodrug of phenobarbital[2], nevertheless it is superior against tremor [3] [4] Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner

ATC

antiepileptic drugs


primidone
[5]

[6]

Links

Interactions between antiepileptic drugs, and between antiepileptic drugs and other drugs

Factors Associated with Ordering Laboratory Monitoring of High-Risk Medications

Q420383 at Wikidata  Interwiki via Wikidata


Notes

  1. ↑ Practice Parameter:Therapies for essential tremor Report of the Quality Standards Subcommittee of the American Academy of Neurology
  2. ↑ The history of barbiturates a century after their clinical introduction
  3. ↑ Essential Tremor: What We Can Learn from Current Pharmacotherapy
  4. ↑ Molecular Mechanisms of Antiseizure Drug Activity at GABAA Receptors
  5. ↑ http://www.whocc.no/atc_ddd_index/?code=N03AA03
  6. ↑ Chronic high-cumulative doses have shown to increase the fracture risk in a dose-dependent manner
Retrieved from "https://en.wikisage.org/w/index.php?title=Primidone&oldid=5198"