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Post-viral fatigue syndrome

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Disease classification WHO
G93.3 Postviral fatigue syndrome

Post-viral fatigue syndrome (PVFS) is a condition that presents a fatigue state resulting from a viral infection. The term is not widely used, but the state of prolonged or severe fatigue after illness is not uncommon. Some people experience fatigue and related symptoms for months or years following a severe viral infection.[1]

Classification

In the WHO's ICD10, PVFS is a group header within 'other disorders of the brain', a neurological category. It is furthermore explicitly excluded from neurotic disorders. Listed under PVFS is benign myalgic encephalomyelitis.[2] Several alternative diagnoses to ME such as chronic fatigue syndrome (CFS) and neuromyasthenia are included in the alphabetic list of the ICD10.

Forms of cancer have also been shown to be post-viral.[3]

Post-viral syndromes may also include post-polio syndrome and multiple sclerosis.

Some researchers claim that post-viral fatigue syndrome is a biological state of weakness or activation of, or damage to the immune system,[4] and that it is common to many post-viral syndromes.

Risk factors

Research indicates that that the chance of developing a post-viral fatigue syndrome is more strongly related to the severity of the infection rather than to demographic, psychological or microbiological characteristics.[1]

See also

Some non-viral diseases, such as Lyme disease, may lead to similar chronic symptoms.

References

References:
  1. 1.0 1.1 Hickie I, Davenport T, Wakefield D, Vollmer-Conna U, Cameron B, Vernon SD, Reeves WC, Lloyd A; Dubbo Infection Outcomes Study Group (2006), "Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study", British Medical Journal, Sep 16;333(7568):575, pmid=16950834
  2. Ramsay MA (1986), "Postviral Fatigue Syndrome. The saga of Royal Free disease", London, ISBN 0-906923-96-4
  3. Zue Hausen H (2002), "Papillomaviruses and cancer: from basic studies to clinical application", Nat Rev Cancer, May;2(5):342-50, Nat Rev Cancer. 2002 May;2(5):342-50
  4. Hyde BM (ed.), "The Clinical and Scientific Basis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome", Nightingale Research Foundation, Ottawa, Canada, with editorial and conceptual advice from Levine P and Goldstein J, ISBN 0-9695662-0-4