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Phenobarbitone

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or phenobarbital is a WHO recommended AED

phenobarbital induces enzymes of the cytochrome P450 system; like phenytoin, carbamazepine, and primidone.[1]

Osteomalacia

The Impact of Anti-Epileptic Drugs on Growth and Bone Metabolism

antiepileptic drug-induced bone loss in young male patients who have seizures

Status epilepticus

Treatment of Established Status Epilepticus

Post encephalitic epilepsy

Effect of Antiepileptic Drugs for Acute and Chronic Seizures in Children with Encephalitis

  • Lin K-L, Lin J-J, Hsia S-H, Chou M-L, Hung P-C, Wang H-S, et al. (2015) Effect of Antiepileptic Drugs for Acute and Chronic Seizures in Children with Encephalitis. PLoS ONE 10(10): e0139974. doi:10.1371/journal.pone.0139974

Uses

Human

Veterinary

ATC

FLexikon:Phenobarbital

  1. http://www.jfmpc.com/text.asp?2016/5/2/248/192338 Arora E, Singh H, Gupta YK. Impact of antiepileptic drugs on bone health: Need for monitoring, treatment, and prevention strategies. J Family Med Prim Care [serial online] 2016 [cited 2016 Nov 28];5:248-53.