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Phenobarbitone: Difference between revisions

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or phenobarbital is a WHO recommended  AED
(BAN) or phenobarbital is a WHO recommended  [[antiepileptic drug|AED]]
<gallery>File: Phenobarbital3d updated.png</gallery>
<gallery>File: Phenobarbital3d updated.png</gallery>
phenobarbital induces enzymes of the cytochrome P450 system; like phenytoin, carbamazepine, and primidone.<ref>http://www.jfmpc.com/text.asp?2016/5/2/248/192338 Arora E, Singh H, Gupta YK. Impact of antiepileptic drugs on bone health: Need for monitoring, treatment, and prevention strategies. J Family Med Prim Care [serial online] 2016 [cited 2016 Nov 28];5:248-53.</ref>
phenobarbital induces enzymes of the [[cytochrome P450]] system; like phenytoin, [[carbamazepine]], and [[primidone]].<ref>[http://www.jfmpc.com/text.asp?2016/5/2/248/192338 Arora E, Singh H, Gupta YK. Impact of antiepileptic drugs on bone health: Need for monitoring, treatment, and prevention strategies. J Family Med Prim Care (serial online) 2016 (cited 2016 Nov 28);5:248-53.]</ref>
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000640/pdf/ijms-17-01242.pdf The Impact of Anti-Epileptic Drugs on Growth and Bone Metabolism


https://www.ncbi.nlm.nih.gov/pubmed/12020260 antiepileptic drug-induced bone loss in young male patients who have seizures
==Osteomalacia==
 
[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000640/pdf/ijms-17-01242.pdf The Impact of Anti-Epileptic Drugs on Growth and Bone Metabolism]
 
[https://www.ncbi.nlm.nih.gov/pubmed/12020260 antiepileptic drug-induced bone loss in young male patients who have seizures]
 
==[[Status epilepticus]]==
[http://www.mdpi.com/2077-0383/5/5/49/htm Treatment of Established Status Epilepticus]
 
==Post encephalitic [[epilepsy]]==
[http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139974 Effect of Antiepileptic Drugs for Acute and Chronic Seizures in Children with Encephalitis]
 
*Lin K-L, Lin J-J, Hsia S-H, Chou M-L, Hung P-C, Wang H-S, et al. (2015) [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139974 Effect of Antiepileptic Drugs for Acute and Chronic Seizures in Children with Encephalitis]. PLoS ONE 10(10): e0139974. doi:10.1371/journal.pone.0139974
 
==Cysteinyl leukotrienes==
[http://www.scielo.br/pdf/bjmbr/v49n4/1414-431X-bjmbr-1414-431X20155031.pdf Montelukast reduces seizures in pentylenetetrazol-kindled mice]
 
==Otros==
[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102649/pdf/BRB3-6-e00554.pdf Association between antiepileptic drugs and hepatocellular carcinoma in patients with epilepsy: a population-based case–control study]


==Uses==
==Uses==
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===Veterinary===
===Veterinary===
==ATC==
<ref>https://www.whocc.no/atc_ddd_index/?code=N03AA02</ref>
[http://flexikon.doccheck.com/de/Phenobarbital FLexikon:Phenobarbital]
{{Wikidata|Q407241}}
<references/>
<references/>
[[Category:GABAA_receptor_positive_allosteric_modulators]]

Latest revision as of 17:41, 21 November 2017