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Nephrotic syndrome
Nephrotic syndrome is a nonspecific kidney disorder characterized by a number of signs of disease: proteinuria, hypoalbuminemia and edema. It is characterized by an increase in permeability of the capillary walls of the glomerulus leading to the presence of high levels of protein passing from the blood into the urine (proteinuria at least 3.5 grams per day per 1.73m<2 body surface area); (> 40 mg per square meter body surface area per hour) low levels of protein in the blood (hypoproteinemia or hypoalbuminemia), ascites and in some cases, edema; high cholesterol (hyperlipidaemia or hyperlipemia) and a predisposition for coagulation[1]
Links
- A randomized trial of cyclosporine in steroid-resitant idiopathic nephrotic syndrome
- The increased risk of coronary heart disease asociated with nephrotic syndrome
- Nephrotic syndrome after infliximab treatment in a patient with ulcerative colitis PDF
- Long-term results of children diagnosed with idiopathic nephrotic syndrome; single center experience
- Marjo Kestila et al. 1998
Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome Molecular Cell 1, 575–582
Therapy
Jacob Churga, Renee Habibb, Richard H.R. Whitec 1970 PATHOLOGY OF THE NEPHROTIC SYNDROME IN CHILDREN: A Report for the International Study of Kidney Disease in Children Lancet 295:1299–1302
- Barman H, Sirie R, Duwarah SG. Effective ultrafiltration with acute peritoneal dialysis in a child with diuretic-resistant nephrotic edema. Saudi J Kidney Dis Transpl [serial online 2015 [cited 2015 Jul 23];26:743-6]