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Nephrotic syndrome: Difference between revisions

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*[http://www.nature.com/ki/journal/v43/n6/pdf/ki1993194a.pdf A randomized trial of cyclosporine in steroid-resitant idiopathic nephrotic syndrome]
*[http://www.nature.com/ki/journal/v43/n6/pdf/ki1993194a.pdf A randomized trial of cyclosporine in steroid-resitant idiopathic nephrotic syndrome]
*[http://www.nature.com/ki/journal/v44/n3/pdf/ki1993292a.pdf The increased risk of coronary heart disease asociated with nephrotic syndrome]
*[http://www.nature.com/ki/journal/v44/n3/pdf/ki1993292a.pdf The increased risk of coronary heart disease asociated with nephrotic syndrome]
*[http://www.jgld.ro/2015/2/22.html Nephrotic syndrome after infliximab treatment in a patient with ulcerative colitis]
*[http://www.jgld.ro/2015/2/22.html Nephrotic syndrome after infliximab treatment in a patient with ulcerative colitis] [http://www.jgld.ro/2015/2/22.pdf PDF]
*Marjo Kestila et al. 1998
*Marjo Kestila et al. 1998
[http://ac.els-cdn.com/S109727650080057X/1-s2.0-S109727650080057X-main.pdf?_tid=0a18bbac-3194-11e5-a6b7-00000aacb360&acdnat=1437694939_00734d3bc1e2a2b3d33dbf834665b445 Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome ] Molecular Cell 1, 575–582
[http://ac.els-cdn.com/S109727650080057X/1-s2.0-S109727650080057X-main.pdf?_tid=0a18bbac-3194-11e5-a6b7-00000aacb360&acdnat=1437694939_00734d3bc1e2a2b3d33dbf834665b445 Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome ] Molecular Cell 1, 575–582

Revision as of 00:01, 24 July 2015

Disease classification WHO
N04 Nephrotic syndrome

Nephrotic syndrome is a nonspecific kidney disorder characterized by a number of signs of disease: proteinuria, hypoalbuminemia and edema. It is characterized by an increase in permeability of the capillary walls of the glomerulus leading to the presence of high levels of protein passing from the blood into the urine (proteinuria at least 3.5 grams per day per 1.73m<2 body surface area); (> 40 mg per square meter body surface area per hour) low levels of protein in the blood (hypoproteinemia or hypoalbuminemia), ascites and in some cases, edema; high cholesterol (hyperlipidaemia or hyperlipemia) and a predisposition for coagulation[1]

Links

Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome Molecular Cell 1, 575–582

Therapy

Jacob Churga, Renee Habibb, Richard H.R. Whitec 1970 PATHOLOGY OF THE NEPHROTIC SYNDROME IN CHILDREN: A Report for the International Study of Kidney Disease in Children Lancet 295:1299–1302

Notes