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Nephrotic syndrome: Difference between revisions
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[http://ac.els-cdn.com/S109727650080057X/1-s2.0-S109727650080057X-main.pdf?_tid=0a18bbac-3194-11e5-a6b7-00000aacb360&acdnat=1437694939_00734d3bc1e2a2b3d33dbf834665b445 Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome ] Molecular Cell, Vol. 1, 575–582 | [http://ac.els-cdn.com/S109727650080057X/1-s2.0-S109727650080057X-main.pdf?_tid=0a18bbac-3194-11e5-a6b7-00000aacb360&acdnat=1437694939_00734d3bc1e2a2b3d33dbf834665b445 Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome ] Molecular Cell, Vol. 1, 575–582 | ||
[[nl:Nefrotisch syndroom]] | [[nl:Nefrotisch syndroom]] | ||
===Therapy=== | |||
Jacob Churga, Renee Habibb, Richard H.R. Whitec | |||
1970 | |||
[http://www.sciencedirect.com/science/article/pii/S0140673670919057 PATHOLOGY OF THE NEPHROTIC SYNDROME IN CHILDREN: A Report for the International Study of Kidney Disease in Children Lancet] 295:1299–1302 | |||
==Notes== | ==Notes== | ||
<references/> | <references/> | ||
Revision as of 23:47, 23 July 2015
Nephrotic syndrome is a nonspecific kidney disorder characterized by a number of signs of disease: proteinuria, hypoalbuminemia and edema. It is characterized by an increase in permeability of the capillary walls of the glomerulus leading to the presence of high levels of protein passing from the blood into the urine (proteinuria at least 3.5 grams per day per 1.73m<2 body surface area); (> 40 mg per square meter body surface area per hour) low levels of protein in the blood (hypoproteinemia or hypoalbuminemia), ascites and in some cases, edema; high cholesterol (hyperlipidaemia or hyperlipemia) and a predisposition for coagulation[1]
Links
- A randomized trial of cyclosporine in steroid-resitant idiopathic nephrotic syndrome
- The increased risk of coronary heart disease asociated with nephrotic syndrome
Marjo Kestila et al. 1998
Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome Molecular Cell, Vol. 1, 575–582
Therapy
Jacob Churga, Renee Habibb, Richard H.R. Whitec 1970 PATHOLOGY OF THE NEPHROTIC SYNDROME IN CHILDREN: A Report for the International Study of Kidney Disease in Children Lancet 295:1299–1302