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{{disease|N04|Nephrotic syndrome}}
{{disease|N04|Nephrotic syndrome}}


Nephrotic syndrome is a nonspecific kidney disorder characterized by a number of signs of disease: proteinuria, hypoalbuminemia and edema. It is characterized by an increase in permeability of the capillary walls of the glomerulus leading to the presence of high levels of protein passing from the blood into the urine (proteinuria at least 3.5 grams per day per 1.73m2 body surface area); (> 40 mg per square meter body surface area per hour ) low levels of protein in the blood (hypoproteinemia or hypoalbuminemia), ascites and in some cases, edema; high cholesterol (hyperlipidaemia or hyperlipemia) and a predisposition for coagulation<ref>https://en.wikipedia.org/w/index.php?title=Nephrotic_syndrome&oldid=669864176</ref>
Nephrotic syndrome is a nonspecific kidney disorder characterized by a number of signs of disease: proteinuria, hypoalbuminemia and edema. It is characterized by an increase in permeability of the capillary walls of the glomerulus leading to the presence of high levels of protein passing from the blood into the urine (proteinuria at least 3.5 grams per day per 1.73m2 body surface area); (> 40 mg per square meter body surface area per hour ) low levels of protein in the blood (hypoproteinemia or hypoalbuminemia), ascites and in some cases, edema; high cholesterol (hyperlipidaemia or hyperlipemia) and a predisposition for coagulation<ref>{https://en.wikipedia.org/w/index.php?title=Nephrotic_syndrome&oldid=669864176 WIKIPEDIA:]</ref>
==Links==
==Links==


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*[http://www.nature.com/ki/journal/v44/n3/pdf/ki1993292a.pdf The increased risk of coronary heart disease asociated with nephrotic syndrome]
*[http://www.nature.com/ki/journal/v44/n3/pdf/ki1993292a.pdf The increased risk of coronary heart disease asociated with nephrotic syndrome]


Marjo Kestila et al. 1998
[http://ac.els-cdn.com/S109727650080057X/1-s2.0-S109727650080057X-main.pdf?_tid=0a18bbac-3194-11e5-a6b7-00000aacb360&acdnat=1437694939_00734d3bc1e2a2b3d33dbf834665b445 Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome ] Molecular Cell, Vol. 1, 575–582
[[nl:Nefrotisch syndroom]]
[[nl:Nefrotisch syndroom]]


==Notes==
==Notes==
<references/>
<references/>

Revision as of 23:42, 23 July 2015

Disease classification WHO
N04 Nephrotic syndrome

Nephrotic syndrome is a nonspecific kidney disorder characterized by a number of signs of disease: proteinuria, hypoalbuminemia and edema. It is characterized by an increase in permeability of the capillary walls of the glomerulus leading to the presence of high levels of protein passing from the blood into the urine (proteinuria at least 3.5 grams per day per 1.73m2 body surface area); (> 40 mg per square meter body surface area per hour ) low levels of protein in the blood (hypoproteinemia or hypoalbuminemia), ascites and in some cases, edema; high cholesterol (hyperlipidaemia or hyperlipemia) and a predisposition for coagulation[1]

Links


Marjo Kestila et al. 1998 Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome Molecular Cell, Vol. 1, 575–582

Notes