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Lamotrigine

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Lamotrigine an AED and antidepressant effective in focal epilepsies, such as rolandic epilepsy [1]lamotrigine has also been found effective in the treatment of bipolar disorder being more efficacious in treating the depressive phase of the illness[2] Lamotrigine inhibits the voltage-gated sodium and calcium channels[3] Rhabdomyolisis has been reported in a case of bipolar disorder by overdose of the lamotrigine [4]

Links

A Randomized Double-Blind Placebo-Controlled Study to Compare Preemptive Analgesic Efficacy of Novel Antiepileptic Agent Lamotrigine in Patients Undergoing Major Surgeries


[https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0041-108911.pdf Neurologische Erkrankungen und Schwangerschaft – eine Übersicht]