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Lamotrigine: Difference between revisions
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Lamotrigine an [[antiepileptic drug|AED]] and antidepressant | Lamotrigine an [[antiepileptic drug|AED]] and antidepressant | ||
effective in focal epilepsies, such as rolandic epilepsy | effective in focal epilepsies, such as rolandic epilepsy | ||
<ref>[http://ugeskriftet.dk/videnskab/atypisk-femurfraktur-hos-en-kvinde-i-behandling-med-lamotrigen]</ref><ref> | <ref>[http://ugeskriftet.dk/videnskab/atypisk-femurfraktur-hos-en-kvinde-i-behandling-med-lamotrigen]</ref>lamotrigine has also been found effective in the treatment of bipolar disorder being more efficacious in treating the depressive phase of the illness<ref> | ||
[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615936/pdf/fphar-06-00242.pdf Management of bipolar depression with lamotrigine: an antiepileptic mood stabilizer] | [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615936/pdf/fphar-06-00242.pdf Management of bipolar depression with lamotrigine: an antiepileptic mood stabilizer]</ref> | ||
</ref> | |||
Lamotrigine inhibits the voltage-gated sodium and calcium channels<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791905/ A Randomized Double-Blind Placebo-Controlled Study to Compare Preemptive Analgesic Efficacy of Novel Antiepileptic Agent Lamotrigine in Patients Undergoing Major Surgeries]</ref> | Lamotrigine inhibits the voltage-gated sodium and calcium channels<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791905/ A Randomized Double-Blind Placebo-Controlled Study to Compare Preemptive Analgesic Efficacy of Novel Antiepileptic Agent Lamotrigine in Patients Undergoing Major Surgeries]</ref> | ||
Rhabdomyolisis has been reported in a case of bipolar disorder by overdose of the lamotrigine | Rhabdomyolisis has been reported in a case of bipolar disorder by overdose of the lamotrigine | ||
Revision as of 18:55, 15 April 2016
Lamotrigine an AED and antidepressant effective in focal epilepsies, such as rolandic epilepsy [1]lamotrigine has also been found effective in the treatment of bipolar disorder being more efficacious in treating the depressive phase of the illness[2] Lamotrigine inhibits the voltage-gated sodium and calcium channels[3] Rhabdomyolisis has been reported in a case of bipolar disorder by overdose of the lamotrigine [4]
Links
[https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0041-108911.pdf Neurologische Erkrankungen und Schwangerschaft –
eine Übersicht]
- ↑ [1]
- ↑ Management of bipolar depression with lamotrigine: an antiepileptic mood stabilizer
- ↑ A Randomized Double-Blind Placebo-Controlled Study to Compare Preemptive Analgesic Efficacy of Novel Antiepileptic Agent Lamotrigine in Patients Undergoing Major Surgeries
- ↑ Rhabdomyolysis after lamotrigine overdose: a case report and review of the literature