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Eslicarbazepine

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is an AED. Adjunctive eslicarbazepine led to seizure reduction in two patients with severe myoclonic epilepsy of infancy[1]

Pharmacy and chemistry

Eslicarbamazepine acetate is an once-daily antiepileptic that was approved in 2009 by the EMA (Zerebix TM) and recently by the American FDA[2] Eslicarbamazepine is the prodrug of S-licarbazepine, both oxcarbazapine and eslicarbazepine metabolize same, different to carbazepine; the latter catabolizes to CBZ 10,11-epoxide (Hainzl et al, 2001)

  1. Severe myoclonic epilepsy of infancy: Seizure reduction during adjunctive eslicarbazepine in two cases
  2. A review of the efficacy and safety of eslicarbazepine acetate in the management of partial-onset seizures