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Difference between revisions of "Epilepsy"

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[[West's syndrome]]

Latest revision as of 02:16, 6 December 2017

Classification of ethiology could divided in four categories:

[1] It is difficult to distinguish between genetic and cryptogenic syndromes.

Morbility data is difficult to interpret when WHO[2] states 50-70 millions persons[3] suffers epilepsy[4]

nonadherence appears to be associated with increased health care costs, nevertheless XR-medicine appears as strategy to overcome compliance with AED[5]

Medicines

type  ,,, ,,,,
INN  Generic slow release
carbamazepine  normal xr
lamotrigine  normal Lamictal XR[6]
levetiracetam  normal xr
oxcarbazepine  oxcarbazepine xr
phenytoin  ... xr
valproate  xr
topiramate  xr

AED

A review of the efficacy and safety of eslicarbazepine acetate in the management of partial-onset seizures

Eslicarbazepine acetate for the treatment of focal epilepsy:an update on its proposed mechanisms of action

In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein

Diverse Mechanisms of Antiepileptic Drugs in the Development Pipeline


ILAE Classification

[7] [8] [9] [10] ILAE Overview

See also

A new perspective for Epileptic Disorders

Links

Q41571 op Wikidata  Interwiki via Wikidata

Epilepsies: diagnosis and management clinical guide

Prevalence and cost of nonadherence with antiepileptic drugs in an adult managed care population

The Efficacy of Leviteracetam versus Carbamazepine for Epilepsy: A Meta-Analysis

The intrinsic severity hypothesis of pharmacoresistance to antiepileptic drugs

Models of epilepsy


purinergic signalling:therapeutic developments


Electroencephalography in the Diagnosis of Genetic Generalized Epilepsy Syndromes

Ranking the Leading Risk Factors for Sudden Unexpected Death in Epilepsy

Lennox-Gastaut Syndrome

Dravet's syndrome

Status epilepticus

Panayiotopoulos syndrome
epilepsia partialis continua

West's syndrome

Ohtahara syndrome

Pretzel syndrome

Doose syndrome

References

References:
  1. The etiologic classification of epilepsy
  2. http://www.who.int/en/
  3. (Li et al 2014)
  4. (Chung 2015)
  5. (Davis et al 2008)
  6. http://www.rxlist.com/lamictal-xr-drug.htm
  7. http://www.who.int/mediacentre/factsheets/fs999/en/
  8. epilepsy is not resolved. Epilepsy Currents 14 2014
  9. https://www.ligaepilepsia.cl/epilepsias/tipos-de-epilepsia
  10. Annie T Berg et al.2010 Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005–2009 Epilepsia 51 676-685