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Drisapersen: Difference between revisions
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An exon skipping experimental [[drug|Medicine]]<ref>https://web.archive.org/web/20120729012249/http://www.prosensa.eu/technology-and-products/pipeline/pro051gsk2402968</ref> | An exon skipping experimental [[drug|Medicine]]<ref>https://web.archive.org/web/20120729012249/http://www.prosensa.eu/technology-and-products/pipeline/pro051gsk2402968</ref> | ||
<ref>https://www.whocc.no/atc_ddd_index/?code=M09AX04</ref> | <ref>https://www.whocc.no/atc_ddd_index/?code=M09AX04</ref> | ||
PRO051/GSK2402968 is considered an orphan drug | PRO051/GSK2402968 is considered an orphan drug. | ||
'''Drisapersen''' | |||
differs from eteplirsen in that it is an 18-mer 2′O-methyl phosphorothioate type of AO, which is negatively charged <ref>[https://www.dovepress.com/eteplirsen-in-the-treatment-of-duchenne-muscular-dystrophy-peer-reviewed-fulltext-article-DDDT Eteplirsen in the treatment of Duchenne muscular dystrophy]</ref> | |||
==Links== | |||
[[Duchenne muscular distrophy]] | [[Duchenne muscular distrophy]] | ||
[http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2019;volume=67;issue=3;spage=717;epage=723;aulast=Arora Duchenne muscular dystrophy: Still an incurable disease] | [http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2019;volume=67;issue=3;spage=717;epage=723;aulast=Arora Duchenne muscular dystrophy: Still an incurable disease] | ||
Latest revision as of 23:42, 11 September 2019
An exon skipping experimental Medicine[1] [2] PRO051/GSK2402968 is considered an orphan drug. Drisapersen differs from eteplirsen in that it is an 18-mer 2′O-methyl phosphorothioate type of AO, which is negatively charged [3]
Links
Duchenne muscular dystrophy: Still an incurable disease
Eteplirsen a 30-nucleotide phosphorodiamidate morpholino oligomer
References: |