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Carbamazepine: Difference between revisions

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<ref>Halliwell RA, Bhardwaj RM, Brown C, Briggs NEB, Dunn J, Robertson J,Nordon A, Florence AJ, Spray drying as a reliable route to produce metastable carbamazepine form IV, Journal of Pharmaceutical Sciences (2017), doi: 10.1016/j.xphs.2017.03.045.</ref>
<ref>Halliwell RA, Bhardwaj RM, Brown C, Briggs NEB, Dunn J, Robertson J,Nordon A, Florence AJ, Spray drying as a reliable route to produce metastable carbamazepine form IV, Journal of Pharmaceutical Sciences (2017), doi: 10.1016/j.xphs.2017.03.045.</ref>
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[[spina bifida]]
Carbamazepine teratogenicity is relatively specific to spina bifida, though the risk is less than with [[valproate|valproic acid]]<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996546/]</ref>


Carbamazepine teratogenicity is relatively specific to [[spina bifida]], though the risk is less than with [[valproate|valproic acid]]<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996546/]</ref>
<ref>[http://www.scielosp.org/pdf/spm/v54n6/a06v54n6.pdf Malformaciones congenitas en hijos de madres epilépticas con y sin tratamiento con anticonvulsivantes]</ref>
<ref>[http://www.scielosp.org/pdf/spm/v54n6/a06v54n6.pdf Malformaciones congenitas en hijos de madres epilépticas con y sin tratamiento con anticonvulsivantes]</ref>


[[Stevens-Johnson syndrome]]<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372085/ HLA-B*15:21 and carbamazepine-induced Stevens-Johnson syndrome: pooled-data and in silico analysis.]</ref><ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296452/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296452/ Carbamazepine-induced Life-threatening Stevens-Johnson Syndrome and Agranulocytosis: The Maiden Case]</ref>
[[Stevens-Johnson syndrome]]<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372085/ HLA-B*15:21 and carbamazepine-induced Stevens-Johnson syndrome: pooled-data and in silico analysis.]</ref><ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296452/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296452/ Carbamazepine-induced Life-threatening Stevens-Johnson Syndrome and Agranulocytosis: The Maiden Case]</ref>
<ref>
<ref>https://www.drugs.com/monograph/carbamazepine.html</ref>
https://www.drugs.com/monograph/carbamazepine.html</ref>


"there is any association between sexual dysfunctions and various AEDs in the treatment, except for carbamazepine (CBZ)"
"there is any association between sexual dysfunctions and various AEDs in the treatment, except for carbamazepine"
<ref>[https://www.ncbi.nlm.nih.gov/pubmed/28315500 Relation between sexual dysfunctions and epilepsy, type of epilepsy, type of antiepileptic drugs: a prospective study]</ref>
<ref>[https://www.ncbi.nlm.nih.gov/pubmed/28315500 Relation between sexual dysfunctions and epilepsy, type of epilepsy, type of antiepileptic drugs: a prospective study]</ref>



Revision as of 04:13, 5 May 2017

structure related to imipraminminiature

can form five polymorphic states, with low water solubility [1]

Carbamazepine teratogenicity is relatively specific to spina bifida, though the risk is less than with valproic acid[2] [3]

Stevens-Johnson syndrome[4][5] [6]

"there is any association between sexual dysfunctions and various AEDs in the treatment, except for carbamazepine" [7]

Links

Spray drying as a reliable route to produce metastable carbamazepine form IV

Antiepileptic Drugs Impair Shortening of Isolated Cardiomyocytes

Transient Splenial Lesion Following Abrupt Withdrawal of Carbamazepine

The Investigation of Insulin Resistance in Two Groups of Epileptic Patients Treated with Sodium Valproate and Carbamazepine

Rapamycin

Evaluating the Effectiveness of GTM-1, Rapamycin, and Carbamazepine on Autophagy and Alzheimer Disease

Extended release

The effects of carbamazepine on prefrontal activation in manic youth with bipolar disorder