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Clozapine: Difference between revisions
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Cloxapine is a prodrug, nor derivative is the active drug. | Cloxapine is a prodrug, nor derivative is the active drug. Clozapine has had strong mood-stabilizing properties<ref>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535045/pdf/10.1177_2045125315584871.pdf</ref> | ||
Cardiovascular side effects of antipsychotic drugs include orthostatic hypotension, syncope, long QTc, ventricular tachycardia, myocarditis, cardiomyopathy, pericarditis, and sudden cardiac death, considering it is metabolized by cytochrome P450, smoking cessation could increase toxicity of the antipsychotic agent<ref> http://www.turkpsikiyatri.com/en/default.aspx?modul=article&id=998</ref> | Cardiovascular side effects of antipsychotic drugs include orthostatic hypotension, syncope, long QTc, ventricular tachycardia, myocarditis, cardiomyopathy, pericarditis, and sudden cardiac death, considering it is metabolized by cytochrome P450, smoking cessation could increase toxicity of the antipsychotic agent<ref> http://www.turkpsikiyatri.com/en/default.aspx?modul=article&id=998</ref> | ||
Revision as of 18:47, 16 September 2015
Cloxapine is a prodrug, nor derivative is the active drug. Clozapine has had strong mood-stabilizing properties[1] Cardiovascular side effects of antipsychotic drugs include orthostatic hypotension, syncope, long QTc, ventricular tachycardia, myocarditis, cardiomyopathy, pericarditis, and sudden cardiac death, considering it is metabolized by cytochrome P450, smoking cessation could increase toxicity of the antipsychotic agent[2]